Director, Therapeutic Area Biomarker Lead (Neuroscience)

DTX Pharma, a Novartis Company
DTX Pharma, a Novartis Company

Basel, Switzerland

Posted on Jul 9, 2026

Salary Range:

CHF142,100.00 - CHF263,900.00


Band

Level 6


Job Description Summary

Office Location: Basel, Switzerland
#LI-Hybrid Hybrid (12 days per month on-site)

Relocation Support: Novartis is unable to offer relocation support - please only apply if this location is accessible to you

About this role:
Make a meaningful impact where science meets patient care—join us in shaping the future of neuroscience. As Director, TABL (Neuroscience), you’ll play a key role in bringing innovative therapies closer to patients by translating scientific discovery into real-world clinical impact. You’ll work alongside passionate, cross-functional teams across research, development, and data science, contributing your expertise to advance precision medicine across a diverse portfolio. This is an exciting opportunity to grow your influence, lead with purpose, and help unlock new possibilities for patients while collaborating in a supportive and forward-thinking environment.


Job Description

Major Accountabilities:

  • Accountable for development and implementation of the biomarker strategy for a portfolio of program(s)/disease indication and coordinates biomarker and diagnostics related elements for clinical projects as appropriate in close collaboration with research, development, precision medicine and commercial

  • Identifies potential project hurdles, provides solutions and establishes contingency plans. Represents Biomarker Development (BMD) on Biomedical Research (BR) or Development project team(s)

  • Responsible for supervising, training, and mentoring of Biomarker Experts, and to ensure line function excellence with respect to administrative efficiency, scientific and technical achievement

  • Proactively contributes expert biomarker input into key clinical and regulatory documents including clinical study protocols, clinical study reports, investigator brochures, Investigational New Drug application (IND) / Investigational Medicinal Product Dossiers (IMPDs) and New Drug Application/Biologics License Applications within agreed timelines and addresses all regulatory requirements with minimal supervision

  • Responsible for the biomarker component of study protocols, reports, project summaries and development plans within agreed timelines and which meet regulatory requirements. Prepare appropriate responses to Health Authority questions (globally)

  • Leads/co-leads Translational Data Science Committee (TDSC) and analytical clusters as relevant to their disease areas or asset, oversees biomarker analyses together with the biomarker sub team and integrates, interprets and reports data to project teams and other customers

  • Leads Biomarker sub-teams and coordinates with appropriate sub-team members and ensures implantation of project strategy and/or prepares summary documentation

  • Maintains and enhances technical and drug development expertise (e.g. training courses, external meeting attendance), and trains other BMD associates. May act as technical / scientific subject matter expert in key BMD related area

  • Publishes internally and/or externally as main contributor; patent applications; reviews current literature in own discipline and related areas and proactively shares

Role Requirements:

  • Doctor of Philosophy or Doctor of Pharmacy with strong background in biomarker development or related biological sciences

  • Minimum eight to ten years’ experience in drug development functions such as biomarker or translational science

  • At least five years’ experience within a relevant line function in industry, academia, or regulatory agency

  • Extensive knowledge of disease biomarkers, pharmacology, and pharmacokinetic and pharmacodynamic evaluation

  • Strong understanding of regulatory requirements and experience supporting clinical and regulatory documentation

  • Demonstrated success leading and influencing multidisciplinary global project teams, with strong negotiation skills

  • Proven leadership with strong coaching, mentoring, and people management capabilities

  • Fluent in English, both spoken and written; additional languages are an advantage

  • Excellent organizational and project skills

  • Strong coaching, mentoring and people management skills

Ready to make a meaningful impact in neuroscience and help bring innovative therapies to patients? We would love to hear from you—apply today and join us in shaping the future of medicine.

Benefits & Rewards

At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.

Expected Annual Base Salary Range for role: CHF 142,100 - 263,900

The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.

In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. Long-term equity awards granted at group level may also be part of your package. Further details will be provided during the application process.

The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.

Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.

Read our brochure to learn more about our global total rewards offering:

https://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdf

Note: Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable. A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the application process.

Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a
position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.


Skills Desired

Analytical Skill (Inactive), Analytical Skill (Inactive), Analytical Thinking, Chemical Biology, Chemistry, Clinical Research, Clinical Trials, Collaboration, Communication Skills (Inactive), Curious Mindset, Data (Inactive), Data Analysis, Decision Making, Design of Experiments (DOE), Detail-Oriented, Drug Development, Drug Discovery Process, Ethics, Gene Therapy- Leadership (Inactive), Influence (Inactive), Laboratory (Inactive), Leading Project Teams, Lifesciences (Inactive), Machine Learning (ML), Medical Research {+ 11 more}