Summary: Typewriter Therapeutics, Inc., Japan (Typewriter TX Japan GK) repurposes a class of genetic elements from various natural genomes and aims to develop an all-RNA-mediated gene writing platform via nonviral delivery to address unmet therapeutic needs. We are seeking a dedicated scientist to join our growing theme and work on this new frontier technology in genome engineering. Reporting to the Sr./Principal Scientist, this scientist will join a collaborative and fun team. She/he is expected to be skilled in molecular and cell biology techniques and displays an interest and aptitude in contributing to a rigorous scientific tone for our group. Prior experiences in primary human cells (such as primary human hepatocytes) are desired. The successful applicant will have high growth potential in a fast-paced startup environment and make crucial contributions to new genome engineering tool development and the new generation human therapeutics. Key Responsibilities- Execute in vitro studies relevant to biological laboratory work (tissue culture, FACS, ELISA, activity assays, in vitro transcription (IVT), PCR and other molecular analytics) for internal programs- Play a central role in generation key data for evaluating gene writing efficiency, mechanism of action for in vitro studies- Design specific constructs, execute assays and identify paths for constant optimization for higher efficacy in primary human cells- Make detailed observations, analyze, and interpret data- Present routinely to diverse audiences including internal research team and other internal/external stakeholders- Be a highly collaborative and energetic team player and a self-directed learner with a keen interest in focused, fast-paced research. Qualifications- BS 8+ or MS 5+ or PhD 1+ years of experience in biological sciences or relevant life sciences-related field.- Molecular biology techniques e.g. nucleic acid extraction, PCR, in vitro transcription- Cell biology techniques including cell culturing, transfection, transduction and flow cytometry- Attention to detail, critical analysis of data, and good troubleshooting ability- Strong written and oral communication skills, interpersonal skills and ability to effectively work as part of a team- Flexible and willing to work across multiple projects- Keep an accurate, comprehensible lab notebook in accordance with company policy- Maintain lab equipment and supplies as needed- Maintain a safe and organized lab bench- Quick learner and team player, communicate with colleagues effectively- Demonstrate good organizational behavior