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RASyn - Scientist/Senior Scientist, Protein Engineering


Boston, MA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Industry: Life Science
  • Post Date: 03/03/2023
  • Website:
  • Company Address: 200 Berkeley Street, 18th Floor, Boston, MA, 02116
  • Salary Range: NA

About RAVen

RAVen (RA Ventures) is the venture-focused arm of RA Capital Management, LP, a Boston-based biotechnology and life sciences investment firm.

Job Description

RASyn, a new biotechnology company launched by RA Capital, is building a proprietary platform of innovative technologies transform the discovery and development of breakthrough therapeutic, diagnostic, and industrial products. RASyn’s platform integrates computational protein design and engineering, machine learning, synthetic biology, and single cell sequencing and will enable cheaper, faster, and larger scale production and optimization of biologics, enzymes, and biomolecule libraries. We are assembling a diverse team of the most talented scientists and innovators who seek to invent the future today and have a passion for solving the most intractable problems.

About RA Capital:

RA Capital funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. TechAtlas' analyses are captured in a unique collection of competitive landscapes, or ‘maps’, that identify competitive therapeutics, diagnostics, research tools, and/or technological capabilities in a given area.

About the Role:

RASyn is seeking an innovative, intellectually curious, and team-oriented Scientist / Senior Scientist in Protein Engineering, who is excited to work on advanced technology development projects at the intersection of protein sciences, synthetic biology, engineering, and microfluidics. In your role as an expert in Protein Engineering at RASyn, you will build, establish, and optimize cell free protein synthesis workflows, as well as contribute to the development of novel assays for high-throughput screening of a wide variety of proteins. You will support our cross-functional teams with your profound knowledge of proteins and be a key contributor supporting our R&D programs. As a member of a rapidly growing and very engaged team, you will have the opportunity to participate in leading cutting-edge research and development, and work with a highly skilled multidisciplinary team in a fast-paced environment.

Key Responsibilities:

  • Design, plan and execute experiments to support research activities, project goals and platform development
  • Implement and optimize Cell Free Protein Synthesis of various proteins into high-throughput screening and production workflows. 
  • Characterize CFPS-produced materials using UPLC, SDS-PAGE, ELISA, and other methods
  • Use automation to support high-throughput activities 
  • Analyze and report experimental results verbally and in writing 

Qualifications & Skills:

  • PhD in biological engineering, biochemistry, synthetic biology, or a related field
  • Demonstrated expertise in implementation, analysis, and optimization of Cell-Free Protein Synthesis systems
  • Experience with high-throughput experimental design
  • Hands-on expertise with current molecular biology techniques including molecular cloning, protein expression, purification, and characterization, and phage display technology
  • Strategic thinker, able to shift seamlessly between rigorous scientific details and high-level context and implications
  • Strong interpersonal skills, with the ability to build strong working relationships with cross-functional teams

Preferred Experience:

  • Industry experience
  • Experience with microfluidics