Job Description

About TRIANA Biomedicines 

TRIANA Biomedicines is a Greater Boston biotechnology company building the leading molecular glue discovery platform to regulate disease targets that are difficult to address with any other modality. TRIANA’s drug discovery engine is powered by high-resolution structural insights, state-of-the-art AI and computational tools, and bespoke chemical libraries. TRIANA’s target-first and rational approach to molecular glue discovery is currently focused on inducing or enhancing the degradation of high-profile cancer targets. The therapeutic approach pioneered by TRIANA has the potential to fundamentally change the paradigm of small molecule drug discovery and bring significant therapeutic benefits to patients. TRIANA is a private company with a top-tier investor syndicate. 

Responsibilities

The candidate will play a critical role within the lead discovery group at TRIANA Biomedicines, and be responsible for advancing critical assays within TRIANA’s glue discovery platform. Primary duties will include the execution, analysis and reporting of cell based assays with a particular focus on degradation, protein:protein: and protein:small molecule interactions. This will involve a diverse array of assay technologies and scales including plate based fluorescence and luminescence assays as well as occasional imaging and other techniques. The candidate will work as part of a highly matrixed team of scientists including biochemistry and disease biology expertise.

Requirements

Qualifications

• Experience in mammalian cell culture and in running cell-based assays for small molecule drug discovery in an industrial setting
• Good understanding of basic in vitro pharmacology principles, experimental design, and rigorous data analysis is required
• Demonstrated ability to work in a fast-paced environment and flexibility to learn new techniques
• Highly effective communicator
• Experience with cell assay development and or targeted protein degradation is an advantage

Education/Experience

Bachelors/Masters Degree in a relevant discipline (Biology, Biochemistry, etc.) and 2-3+ years of relevant post-degree industry experience (Biotech, Pharma, CRO, etc.).

 We welcome applications from skilled individuals whose qualifications may not fit the criteria outlined above.

 Our Culture

Our Team is our greatest asset at TRIANA. We are proud to work with an integrated group of individuals from an extensive range of backgrounds and experiences. Diversity, Equity, Inclusion and Belonging are important aspects of our culture. We embrace our differences and cultivate an environment that drives better collaboration and innovation by striving to ensure that all coworkers have an ongoing positive experience while being their authentic selves.

Our Values

At TRIANA we are empowered to act. We dare to create transformative medicines for patients. Our creativity and dedication are the glue that unites us in pursuit of our mission.