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Sr. Scientist, Analytical Development for Raw Materials


San Carlos, CA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Industry: Vaccine
  • Post Date: 07/09/2024
  • Website:
  • Company Address: 825 Industrial Rd, Suite 300, San Carlos, California 94070, US

About Vaxcyte

Vaxcyte is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases

Job Description

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, periodontitis and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. 
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
*MODEL EXCELLENCE:  The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
Vaxcyte is looking for an energetic and talented individual to join our analytical development team. Primary responsibility for the incumbent will include method development, sample testing and data analysis, protocol and report authorization, and analytical method transfer oversight and coordination. 

Essential Functions:

    • Independently perform method development across a broad range of analytical methods for raw materials for QC and characterization purpose to support pre-clinical and clinical projects.
    • Oversee method transfer to external contract testing labs; Design and perform studies to assist troubleshooting of QC testing, method qualification/validation or issues related to the methods as needed.
    • Perform analytical testing, data analysis and interpretation and present in various project and functional team meetings.
    • Collaborate with cross-functional teams to achieve project timelines and goals.
    • Maintain thorough and accurate records of laboratory work.
    • Author analytical documents including but not limited to test method, protocols, and reports.


    • PhD in Analytical Chemistry, Biochemistry or a related field with 3+ years of industry experience; MS or BS with 8+ years of industry experience in Pharma/Biotech.
    • Extensive hands-on experience in a wide range of analytical techniques, such as UV-Vis,  HPLC, CE, SDS-PAGE, icIEF, LCMS, GCMS, enzyme kinetics, colorimetric and fluorescent plate-based assays, ELISA, Western Blot, etc.
    • Adeptness in learning: given the broad range of molecular structures and analytical methods involved, the ability to quickly learn and adapt to new techniques and technologies is paramount.
    • Ability to analyze complex problems, identify potential solutions, and make informed decisions is critical for the success of this role.
    • Familiar with regulatory standards and quality systems (e.g., GLP, GMP).
    • Ability to work in a fast-paced team environment, and to consistently meet aggressive timelines while prioritizing tasks for multiple projects.
    • Must communicate complex scientific concepts clearly and precisely to a variety of audiences, including junior scientists, cross-functional teams, and non-scientific stakeholders.
    • Effective communication and interpersonal skills, with the ability to collaborate cross-functionally and work effectively in a team environment.
    • This position is a lab-based role and requires onsite presence.
    • All Vaxcyte employees require vaccination against COVID-19.
Reports to: Associate Director, Analytical Development, Raw Materials
Location: San Carlos, CA
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range: $152,000 – $170,000
Send resumes to:
Vaxcyte, Inc.
825 Industrial Road, Suite 300
San Carlos, CA 94070
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.