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Stealth Startup - Scientist/Sr Scientist, Protein Engineering


Cambridge, MA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Industry: Life Science
  • Post Date: 07/09/2024
  • Website:
  • Company Address: 200 Berkeley Street, 18th Floor, Boston, MA, 02116

About RAVen

RAVen (RA Ventures) is the venture-focused arm of RA Capital Management, LP, a Boston-based biotechnology and life sciences investment firm.

Job Description

Launched by RA Capital, we are a stealth-stage biotechnology company building a modular, next-gen platform to unlock previously unavailable biomolecule design spaces to transform the discovery and development of differentiated therapeutic, diagnostic, and industrial products. Our team is an innovative group of domain experts in AI/ML computational modeling, advanced synthetic biology, microfluidics, protein engineering, and single-cell profiling who are deeply passionate about the power of the platform to invent the future today. World-class scientific founders from the Broad Institute, cutting-edge technology, and backing from RA Capital come together in a dynamic start-up environment.
About RA Capital:
RA Capital funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. TechAtlas' analyses are captured in a unique collection of competitive landscapes, or ‘maps’, which identify competitive therapeutics, diagnostics, research tools, and/or technological capabilities in a given area.
About the Role:
We are seeking an innovative, self-motivated, and team-oriented Scientist in Protein Engineering, with a passion for developing assays to support the interrogation of protein libraries using a variety of display, cellular, and molecular techniques. In your role, you will support the team by executing, analyzing and presenting experiments to drive platform activities and improvements. You will work closely with our cross-functional teams and be a contributor supporting our R&D programs. As a member of a growing and engaged team, you will have the opportunity to take part in leading innovative research and development, and work with a highly skilled multidisciplinary team in a fast-paced startup environment.
Key Responsibilities:
  • Design, construct, and validate protein variant libraries using display techniques for platform activities,
  • Develop novel constructs and assays to explore diverse functionalities using cellular and molecular methods,
  • Leverage NGS and single cell technologies to interrogate libraries and single cell assays,
  • Conduct and support biomolecular experiments with high precision and reliability,
  • Contribute to projects through data generation, analysis, interpretation, and presentation,
  • Maintain detailed electronic lab notebook and registration of constructs and biologics, and
  • Follow Standard Operating Protocols and generate new ones when necessary.
Qualifications & Skills:
  • A PhD in Biochemistry, Biological/Chemical Engineering, Microbiology, Biology or a Master’s degree in a related field with 3+ years of laboratory experience,
  • Expertise in mammalian cell culture, flow cytometry, FACS sorting, protein characterization and protein display technologies,
  • Proficient in common molecular cloning techniques and sequencing (E.g., DNA/RNA isolation, PCR, qPCR, NGS library generation),
  • Some background in immunology is preferred,
  • Strong analytical skills, detail-oriented, and thrives in a fast-paced startup environment,
  • Excellent communication skills (written and verbal) and adept at building strong relationships across teams,
  • Highly adaptable, able to work both independently and collaboratively, and
  • Self-motivated, proactive, and collaborative approach; driven to achieve scientific and business objectives.