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Synolo - Associate Scientist/Scientist, Immuno-oncology


Cambridge, MA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Industry: Life Science
  • Post Date: 04/08/2024
  • Website:
  • Company Address: 200 Berkeley Street, 18th Floor, Boston, MA, 02116

About RAVen

RAVen (RA Ventures) is the venture-focused arm of RA Capital Management, LP, a Boston-based biotechnology and life sciences investment firm.

Job Description

Synolo Therapeutics, an early-stage biotechnology company launched by RA Capital, is pioneering the development of precision-targeted immunotherapies for cancer. Powered by computational protein design and proprietary technologies which yield biological data sets at unprecedented scale and resolution, we are building a pipeline of first-in-class multi-specific biologics with novel functionalities. Synolo was founded by pioneers in the field of protein design and engineering, synthetic biology, DNA sequencing, immunology, and biologics drug discovery and development. 
About RA Capital:

RA Capital Management funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. TechAtlas' analyses are captured in a unique collection of competitive landscapes, or ‘maps’, that identify competitive therapeutics, diagnostics, research tools, and/or technological capabilities in a given area.
About the Role:

Synolo Therapeutics is seeking an innovative, self-motivated, and team-oriented Associate Scientist or Scientist in Immuno-oncology, with a passion for discovering and developing novel medicines and who thrives working in a fast-paced startup environment. In this role, you will help drive innovative multi-specific biologics projects by developing and running immune assays to test drug leads. You will support our cross-functional teams and be a key contributor to our drug discovery and development programs. As a member of a rapidly growing and very creative team, you will help us in our mission to improve patients’ lives and develop novel therapies.

Key Responsibilities:

  • Contribute to and support research activities and project goals for the immuno-oncology group
  • Develop, optimize, and run immune assays to characterize muti-specific biologics leads (ex: ELISA, MSD, flow cytometry, luminescence reporter assays)
  • Generate and maintain cultures and stocks of immortalized cell lines and primary human cell samples (ex: PBMCs)
  • Analyze, summarize, and communicate experimental results verbally and in writing
  • Record data and maintain an electronic lab notebook (ELN)
  • Work collaboratively in a team environment

Qualifications & Skills:

  • Level commensurate with experience:
    • Associate scientist: MS or BA/BS in immuno-oncology, immunology, cell biology, or a related field. MS + 3 years industry experience, BA/BS + 5 years industry experience
    • Scientist: PhD in immuno-oncology, immunology, cell biology, or a related field. PhD with 0+ years, MS with 5+ years, BS with 8+ years industry experience
  • Hands-on experience with immunological techniques, including ELISA, MSD and flow cytometry
  • Hands-on experience with current molecular biology and cell biology techniques, including mammalian cell culture, reporter assays, transfection, and transduction
  • Strong analytical skills, with attention to detail and ability to multi-task
  • Strong interpersonal skills, with the ability to build strong working relationships with cross-functional teams
  • Strong communication skills

Preferred Experience:

  • Hands-on experience with characterizing biologics through cell-based immune assays
  • Hands-on experience with running multi-color flow cytometry
  • Industry experience