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Director, Supply Chain (European Region)

Vaxcyte

Switzerland
  • Job Type: Full-Time
  • Function: Operations
  • Industry: Vaccine
  • Post Date: 04/15/2024
  • Website: www.vaxcyte.com
  • Company Address: 825 Industrial Rd, Suite 300, San Carlos, California 94070, US

About Vaxcyte

Vaxcyte is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases

Job Description

Vaxcyte, Inc. (Nasdaq: PCVX) is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Vaxcyte’s lead candidate, VAX-24, is a 24-valent, broad-spectrum, carrier-sparing pneumococcal conjugate vaccine (PCV) being developed for the prevention of invasive pneumococcal disease (IPD). The Company is re-engineering the way highly complex immunizations are made through modern synthetic techniques, including advanced chemistry and our exclusively licensed XpressCFTM cell-free protein synthesis platform. Unlike conventional cell-based approaches, the Company’s system for producing difficult-to-make proteins and antigens is intended to accelerate its ability to efficiently create and deliver high-fidelity vaccines with enhanced immunological benefits. Vaxcyte’s pipeline also includes VAX-31, a 31-valent PCV candidate; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease; and VAX-GI, a vaccine program designed to prevent Shigella. The Company is driven to eradicate or treat invasive bacterial infections, which have serious and costly health consequences when left unchecked. For more information, visit www.vaxcyte.com.
 
Vaxcyte, headquartered in San Carlos, CA, went public in June 2020 and currently has a team of approximately 180 employees and anticipates continued, significant growth. Following equity offerings in October 2022 and April 2023, which generated over $1.1 billion in net proceeds, the Company’s balance sheet is further strengthened to advance its pipeline of novel vaccines, including VAX-24. These financings followed positive data readouts from Vaxcyte’s Phase 1/2 proof-of-concept study evaluating VAX-24 in adults aged 18-64 and Phase 2 study in adults 65 and older. The Company believes these results support a best-in-class potential for VAX-24, which was designed to replace the current standard-of-care in adults and children. VAX-24 is being investigated for the prevention of IPD, which can be most serious for infants, young children, older adults and those with immune deficiencies or certain chronic health conditions. Given the global impact of pneumococcal disease remains significant, the public health community continues to advocate for vaccines that can offer broader protection to prevent IPD. Vaxcyte’s PCV franchise, consisting of VAX-24 and VAX-31, is designed specifically to address this need and has the potential to deliver the broadest protection for this very serious disease. We believe that our PCVs could receive regulatory approval based on successful completion of clinical studies utilizing well-defined surrogate immune endpoints, consistent with how other PCVs have obtained regulatory approval in the past, rather than requiring clinical field efficacy studies.
 

 

    • Oversee creation of feasible production schedules for DS & intermediates at our Lonza Visp CMO.
    • Schedule delivery of Vaxcyte managed critical raw materials to Lonza Visp.
    • Oversee the Lonza process for ordering commodity raw materials and consumables needed to support Vaxcyte production.
    • Manage inventory of Vaxcyte owned materials in Europe.
    • Ensure that our European partners have robust inventory management procedures.
    • Oversee cycle counts and physical inventory counts.
    • Define and monitor KPIs including delivery performance, yield, cycle time, reject rate and consumption rate.
    • Lead cross functional Operations planning process including Lonza supply chain, Global Supply Chain, MSAT, Strategic Sourcing and QA.
    • Manage our European third-party storage sites.
    • Oversee shipments of product between our European production and storage sites.
    • Own the shipping procedures for material coming out of our European mfg & storage sites.
    • Proactively identify potential supply risks and initiate actions to mitigate.
    • Oversee creation of supply dashboards to help organization understand overall status and risk areas.

Requirements

    • B.S. / B.A. degree or Advanced Degree (preferred).
    • 8 - 12 years’ experience working in pharmaceutical / biotech supply planning
    • Strong Knowledge of GMPs.
    • Strong Experience leading Cross-Functional teams.
    • ·Strong experience managing direct reports.
    • Strong experience working with CMOs and Suppliers of pharma materials.
    • Strong experience with pharma cold chain logistics.
    • Excellent analytic skills.
    • Excellent communication skills.
    • Fluent in English.
    • Fluency in High German and/or Swiss German Highly preferred.
    • All Vaxcyte employees require vaccination against COVID-19.
Reports to: Executive Director, Global Supply Chain
 
Location: Visp, Switzerland
 
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
 
 
Send resumes to:
 
Vaxcyte, Inc.
825 Industrial Road, Suite 300
San Carlos, CA 94070
 
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.